|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Tissue Inhibitor of Metalloproteinase-2
|
|
Descriptor Spanish:
|
|
Inhibidor Tisular de Metaloproteinasa-2
|
|
Descriptor Portuguese:
|
|
Inibidor Tissular de Metaloproteinase-2
|
|
Synonyms English:
|
|
TIMP-2
|
|
Tree Number:
|
|
D12.776.926.500
|
|
Definition English:
|
|
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo. |
|
History Note English:
|
|
1998; see TISSUE INHIBITOR OF METALLOPROTEINASE-2 (NM) 1989-1997
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
33427
|
|
Unique Identifier:
|
|
D019716
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS SciELO LILACS LIS
|